Medically reviewed by Dena Westphalen, Pharm.D. — composed by Rachel Nall, MSN, CRNA on august 29, 2019

You are watching: Can you take pepto bismol with alcohol

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The pink fluid or pink pill that bismuth subsalicylate (commonly recognized by the brand surname Pepto-Bismol) have the right to relieve symptoms choose upset stomach and diarrhea. So when you’ve overdone that on the alcohol, it might sound favor a an excellent plan for easing her stomach woes.

However, there space some factors why Pepto-Bismol and also alcohol may not mix as well as a Jack and also Coke did the night before. Keep analysis for some considerations before reaching because that the Pepto when your stomach hurts.

Pepto’s active ingredient, bismuth subsalicylate, has actually anti-inflammatory properties that minimize the irritation that can reason diarrhea and upset stomach.

The medicine additionally coats the stomach lining, i m sorry acts together a barrier between the stomach lining and the building material that might irritate the stomach, such as stomach acid.

Pepto also has antimicrobial effects. For this reason, physicians prescribe it to treat H. Pyloriinfections the can cause acid reflux and also upset stomach.

Alcohol can irritate the stomach lining and also cause a symptom well-known as gastritis. The condition can cause symptoms such as:

bloating food regurgitation nauseaupper ab pain vomiting

Periodic gastritis native a night that overindulging typically isn’t the bad. However, those who have alcohol usage disorder or regularly binge drink have the right to experience damage due come chronic inflammation in the stomach lining. This can an outcome in ulcers and gastrointestinal (GI) bleeding.

The key reason why Pepto and alcohol nothing mix well is the the liver is (at least in part) responsible because that metabolizing both alcohol and Pepto-Bismol. If the gastrointestinal tract is mostly responsible for soaking up the energetic ingredients in Pepto-Bismol, it’s believed the liver division some down as well.

The potential difficulty with this is if the liver is too busy breaking under one drug, it might not rest the various other down together effectively. This deserve to potentially damage the liver and also extend the quantity of time both Pepto-Bismol and also alcohol are existing in the body.

Doctors additionally worry around the use of Pepto-Bismol and also alcohol if a person has actually ulcers. These are locations of the stomach the aren’t safeguarded by the stomach’s lining, and can an outcome in pain and bleeding. The mix of alcohol and Pepto-Bismol have the right to increase the risks for GI bleeding.

One sign to look at for

If you perform use Pepto to shot and relax your uncomfortable stomach while drinking or ~ drinking, watch her stool because that symptoms that GI bleeding. This can include bright or dark red blood in your stool.

Pepto deserve to turn her stool black, therefore this readjust in shade doesn’t necessarily median you have a problem.

See more: Question 2 Of 20 Which Region Had The Most Cultural Isolation

A most the potential interactions between Pepto-Bismol and alcohol are theoretical. There aren’t a lot of medical reports from civilization who’ve been harmed by the alcohol-and-Pepto combo. Yet there also aren’t any type of studies in the past couple of decades that display taking Pepto after drinking is helpful or safe.

There room a few studies from the 1990s that didn’t report side results from utilizing Pepto and also drinking. One native 1990 published in the journal of global Medical research study studied 132 volunteers that drank come excess and took either Pepto or a placebo.

At the finish of the study, they didn’t find any side impacts from acquisition the medicine and drinking. The participants who took Pepto go report much better symptom relief. Again, this is an enlarge study and one of the couple of that looked in ~ Pepto and also alcohol.

A hangover is the combination of dehydration, irritation to her stomach and also your body’s initiatives to clear the alcohol from her system. Unfortunately, there’s not a lot you can do various other than permit time pass and your body clear the alcohol from your system.

Doctors can not use proven any definitive techniques for curing or increasing a hangover’s symptom — this even consists of studies on giving intravenous (IV) fluids and taking a pains reliever before bed.


You can drink water or various other electrolyte-containing beverages in an attempt to re-hydrate. Yet drinking many of fluids is a healthy and balanced idea even if it is you have a hangover or not.

Eat carefully

Until you feeling better, you can likewise eat bland foods items that aren’t most likely to upset your stomach further. These include:

applesauce bananasbroth plain crackers toast

Get checked after a day

If you nothing feel better after about 24 hours, you may want to watch your physician in situation your symptoms might be connected to another medical condition.